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The laboratory has state-of-the-art imaging equipment:
A 9.4 Tesla, 30 cm bore research magnet equipped with a new Bruker
console with Paravision 4.0 software update. The core’s staff members
develop standard protocols, which users can execute with relatively
little training. The scanner is capable of a variety of state-of-art
experiments including echo-planar imaging, diffusion weighted imaging,
magnetization transfer imaging, and very fast imaging for monitoring
contrast media uptake.
A new Philips Achieva 1.5 Tesla scanner
equipped for parallel imaging. Among the advantages offered by the
Philips scanner are extremely fast imaging and specialized coils for
breast, prostate, pelvis, and spine.
Almost all of the clinical research is
performed on this scanner but two recently upgraded GE scanners are also
available for research.
The upgraded equipment and the new 9.4
Tesla console has expanded and improved the types of imaging offered by
the facility. It now provides a wide variety of anatomic and functional
images including:
Very high resolution (as high as 100
microns in plane) T1 and T2-weighted images
Diffusion and Diffusion Tensor images
Dynamic contrast enhanced MR images with
high spatial and spectral resolution
Very high resolution EPSI for improved
anatomic and functional imaging
Magnetization Transfer images
Spin – tagging and angiograph
A variety of fast imaging methods
including echo-planar imaging and fast spin echo imaging.
The laboratory also has:
A well equipped small-animal surgery and
an electronics laboratory
A Molecular and Physiological Imaging
laboratory in the Radiology Department that the core uses for molecular
biology, cell culture, contrast agent development and preparation.
Physiological monitoring equipment that
measures blood-pressure, ECG, temperature, and oxygen
A number of fast imaging computers and
software for data analysis
Access to time on clinical imaging
equipment in the Goldblatt facility, the Duchossois Center for Advanced
Medicine (DCAM) and the Neurosciences Imaging Center.
The MRIS Core Facility provides the
following services:
Scans of
tissues
Scans of
cells
Scans of
materials
Scans of
animal models of cancer (ie: prostate, mammary, ovary, brain etc)
Scans of
animal models not involved with cancer (ie: cardiac, brain, pancreas,
etc.)
Scans of
patients
These scans provide the following
information:
Detailed
3-D anatomy
Perfusion
Capillary
permeability
Blood
volume
Energy
metabolism
Metabolic
markers for cancer
Measurements of the apparent diffusion constant
T1, T2
measurements.
We also provide a variety of veterinary
services including:
Preparation of animals for MRI experiments
Anesthesia
and respiration
Physiological monitoring
Catheter
implantation
Tumor
implantation
For MRI experiments we perform the
scans for users when necessary and analyze data.
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